Thursday, May 26, 2011

Interesting case - 5.26.2011

Continuing the theme, here is another contribution by my co-fellow, Derek Mathis, MD. It's an interesting case that is not normally considered to fall under the umbrella of neuropathology per se, but it can involve structures that are near and dear to the brain (and rarely the brain parenchyma itself).

This is my last month of my neuropathology fellowship at UTSW. I saved up all of my vacation for the last year, and am taking my family on a road trip to see the West coast and Canadian Rockies for nearly all of June. I'll be bringing my wife and kids to the AANP meeting in Seattle. Afterwards, I'll be joining the Pathology faculty at Loma Linda University (my alma mater) in beautiful Southern California (Yay!!). Needless to say, I won't be posting from our campsites; I'll wait until I'm settled in before resuming. Hope to see some of you in Seattle!

Here's the case...  A 29-year-old male presented to his primary care physician complaining of headache and a mass on his left forehead. Neuroimaging was followed by neurosurgical intervention...

Sagittal T1
Coronal T1 post-gadolinium
H&E; low-magnification
H&E; medium-magnification
H&E; high-magnification
There are immunostains on this case that you'll get to see. First, you should formulate your differential diagnosis and determine what panel of immunostains you would order...

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